Banner-INPACT-DEB

IN.PACT™ Admiral™
Drug-Coated Balloon
 

Beyond the Expected

Balloon-based drug delivery exceeds expectations by providing high drug-in-tissue levels and favorable clinical results.* Our proprietary FreePac coating is a formulation of Paclitaxel and urea, a hydrophilic naturally occurring excipient that provides rapid drug transfer to the vessel wall.

IN.PACT DCB MECHANISM OF ACTION
InPact-Action-Chart

 
PK ANIMAL MEASUREMENTS DEMONSTRATE HIGH INITIAL DRUG UPTAKE AND CAN REMAIN IN THE VESSEL WALL FOR OVER 180 DAYS AT THERAPEUTIC LEVELS.**

InPact-180-Chart

› Paclitaxel resides long-term in the tissue as it forms micro depots. Adventitial washout is slow.

* Thunder, Tepe NEJM 2008.; Kelsch et al, Inv. Radiol. 2011; 46: 255-263.; Schnorr Minerva Cardioangiol 2010;58:567-82.
** Data on file at Medtronic, Inc.

UC201301645i EE